BIOINORGANIC CHEMISTRY A Short Course Second Edition

380 IRON-CONTAINING PROTEINS AND ENZYMES transformation of intermediate [(TMP + • )Fe III (O − )X)], 3 - X, to the possible inte ...

CYTOCHROME P450 : A MONOOXYGENASE 381 The [Fe IV (O)(TMCS)] + complex was synthesized at 90% yield starting with [Fe II (TMCS)] ...

382 IRON-CONTAINING PROTEINS AND ENZYMES the [Fe IV (O)(TMCS)] + (Figure 7.23 , complex 1) did not react with triphenyl- phosphi ...

matter on earth. One website devoted to cytochrome b(6)f is found at http:// http://www.biology.purdue.edu/people/faculty/cramer ...

384 IRON-CONTAINING PROTEINS AND ENZYMES [Fe 2 S 2 ] cluster - binding subdomains have the topology of an incomplete anti- paral ...

The following description of the electron transfer – proton transport scheme is illustrated in Figure 7.26. First, an electron i ...

386 IRON-CONTAINING PROTEINS AND ENZYMES heme b n and heme x, hemes that are contained within the cytochrome b portion of the co ...

histidine ligations effectively crosslink the B and D helices. The unusually connected heme x (see Figure 7.25C ) is covalently ...

388 IRON-CONTAINING PROTEINS AND ENZYMES 7.6 Cytochrome bc 1 : A Bacterial Cytochrome, 7.6.1 Introduction, Cytochrome bc 1 is a ...

CYTOCHROME bc 1 : A BACTERIAL CYTOCHROME 389 as an electron transfer agent, and its reduced alcohol partner, ubiquinol, coQH 2 , ...

390 IRON-CONTAINING PROTEINS AND ENZYMES cytochrome c 1. On the intermembrane side, cytochrome c 1 , the ISP, and subunit 8 sit ...

CYTOCHROME bc 1 : A BACTERIAL CYTOCHROME 391 heart bc 1 complexes^79 (PDB: 1QCR) and for chicken heart cytochrome bc 184 (PDB: 1 ...

392 IRON-CONTAINING PROTEINS AND ENZYMES TABLE 7.6 Metal Cofactor Distances in cytochrome bc : [2Fe – 2S] Position and Mobility ...

CYTOCHROME bc 1 : A BACTERIAL CYTOCHROME 393 PDB No.(reference, date) Species (Crystal Space Group, resolution, Å ) Inhibitor or ...

394 IRON-CONTAINING PROTEINS AND ENZYMES (Nε 2 – Fe = 2.03 Å ) and met160 (S δ – Fe = 2.37 Å ). The heme is covalently anchored ...

CYTOCHROME bc 1 : A BACTERIAL CYTOCHROME 395 Both the N - and C - termini are located in the matrix. The two hemes are bound wit ...

396 IRON-CONTAINING PROTEINS AND ENZYMES tions may result in mitochondrial myopathies, causing neuromuscular disease symptoms. I ...

CYTOCHROME bc 1 : A BACTERIAL CYTOCHROME 397 value of 1.0, iron atoms in the other bc 1 subunits can be compared. For instance, ...

398 IRON-CONTAINING PROTEINS AND ENZYMES to the Q i site (n side, near the matrix space) and inhibits the transfer of elec- tron ...

CYTOCHROME bc 1 : A BACTERIAL CYTOCHROME 399 hydroxyl groups. The closest approach of a UQ2 atom is that of its methoxy oxygen O ...