Advices For Studying Organic Chemistry

Ar CH 3 Ar CH 2 Cl Ar CHCl 2 Ar CCl 3 [ O ] [ H ] [O] [ H ] [ O ] [ H ] When an organic compound is reduced the reducing agent ...

CO Et^2 O 2 2 H LiAlH 4 CH 2 O)Al]Li Li 2 SO 4 H 2 O/H 2 SO 4 CH 2 OH Al 2 (SO 4 ) 3 R [(R 4 H 2 LiAlO 2 Lithium aluminum hydrid ...

C O OH H 2 O 87% no anol H 2 CH 3 C CH 3 H 3 CH 2 C CHCH 3 NaBH 4 2-Buta ne 2-But The key step in the reduction of a carbonyl c ...

2) NaBH 4 reductions can be carried out in water or alcohol solutions. The Chemistry of Alcohol Dehydrogenase When the enzyme a ...

2) nzyme’s protein scaffold is to hold the zinc ion, coenzyme, and 3) eversible and when the relative concentration of ethanol i ...

CO R^2 R^1 re face (when looking at this face there is a clockwise sequence of priorities) si face (when looking at this face th ...

B B B H R-Alpine-BoraneTM B H 9-BBN O HO H (S)-(−)Aline-Borane 97%enantiomeric excess 60-65% yield CH 3 B D O OH H R R C H D (R) ...

BH B OBn OBn B OBn H NB-EnantrideTM Li nopol benzyl ether NB-EnantraneTM t-BuLi 3) Reagents derived from LiAlH 4 and chiral amin ...

12.4 OXIDATION OF ALCOHOLS 12.4A OXIDATION OF PRIMARY ALCOHOLS TO ALDEHYDES: RCH 2 OH → RCHO 1° alcohols can be oxidized to ald ...

3) PCC and PDC are cancer suspect agents and must be dealt with care. One reason for the success of oxidation with PCC is that ...

Various oxidizing agents based on chromium(VI) have been used to oxidize 2° alcohols to ketones. The most commonly used reage ...

A Mechanism for the Reaction Chromate Oxidations: Formation of the Chromate Ester Step 1 C O H 3 C H H 3 C + Cr O − O O H O Cr O ...

(^) 3) The overall result of second step is the reduction of HCrO 4 – to HCrO 3 – , a two electron (2 e–) change in the oxidatio ...

O Cr R C R R O O O OH R C R R H + − O Cr O O OH+ H+ + H 2 O 3°Alcohol This chromate ester cannot undergo elimination of H 2 CrO ...

infrared spectra. The alcohol hydroxyl hydrogen typically produced a broad^1 H NMR signal of variable chemical shift which can ...

character of the C–M bond. 1) Alkylsodium and alkylpotassium compounds are highly reactive and are among the most powerful of ba ...

(Et 2 O) (THF) ii) Most organolithium compounds slowly attack ethers by bringing about an elimination reaction. R :δ− Liδ+ + HCH ...

RX RMgX ArX ArMgX + Mg Et^2 O + Mg Et^2 O Grignard reagents 1) The order of reactivity of halides with magnesium is RI > RBr ...

Mg X R R R O C 6 H 5 R O 1) Complex formation with molecules of ether is an important factor in the formation and stability of G ...

Rδ− MgXδ+ + H R H + R + Mg2+ + X − Grignard reagent (stronger base) Alcohol (stronger acid) Alkane (weaker acid) Alkoxide ion (w ...