Vertebrate Development Maternal to Zygotic Control (Advances in Experimental Medicine and Biology)

415 et al. 2009 ; Kawamura and Sunanaga 2011 ). Circulatory vasa-positive cells have been observed in all botryllid species exam ...

416 8.4.3 De Novo Formation of Germ Cells A handful of studies suggest that in some ascidians, germ cells can be regenerated at ...

417 extirpation of a strip of intermediate mesoderm from early tailbud stage embryos (Humphrey 1927 , 1929 ). The absence of PGC ...

418 to predetermine their fate as PGCs. Indeed, material with the properties of germinal granules, a major component of germ pla ...

419 Building on his seminal discovery of mesoderm induction (Nieuwkoop 1969 ), Nieuwkoop and colleagues began a series of studie ...

420 RNA encoding the germ cell-specific protein dazl, which is a component of Xenopus germ plasm (Houston et al. 1998 ), is not ...

421 without radically affecting the development of somatic cells. The paradigm estab- lished with the axolotl system is defined ...

422 expressing Blimp1 become lineage restricted PGC precursors (Ohinata et al. 2005 ). A subsequent analysis using multicolored ...

423 a/b1, T and Eomes regulatory regions are bound by Blimp1 in PGCs at a time when mRNA transcripts of these targets are reduce ...

424 and Zhao 2001 ; Ohinata et al. 2009 ), and it was shown that their signals are trans- duced via phosphorylated Smads (Chang ...

425 also be derived as naïve pluripotent cells in the presence of a specific MAPK inhibi- tor, a GSK3β inhibitor and LIF (also k ...

426 increasing again by day 28 (Hyldig et al. 2011b). Another study investigating imprinted gene methylation reprogramming in pi ...

427 References al-Mukhtar KA, Web AC (1971) An ultrastructural study of primordial germ cells, oogonia and early oocytes in Xeno ...

428 Boterenbrood EC, Nieuwkoop PD (1973) The formation of the mesoderm in urodelean amphibi- ans: V. Its regional induction by t ...

429 Chiquoine AD (1954) The identification, origin, and migration of the primordial germ cells in the mouse embryo. Anat Rec 118 ...

430 Frankenberg S, Renfree MB (2013) On the origin of POU5F1. BMC Biol 11:56. doi:10.1186/ 1741-7007-11-56 Fujimura M, Takamura ...

431 Heasman J, Quarmby J, Wylie CC (1984) The mitochondrial cloud of Xenopus oocytes: the source of germinal granule material. D ...

432 Hyldig SM, Ostrup O, Vejlsted M, Thomsen PD (2011b) Changes of DNA methylation level and spatial arrangement of primordial g ...

433 Kee K, Reijo Pera RA (2008) Human germ cell lineage differentiation from embryonic stem cells. CSH Protoc 2008:pdb.prot5048. ...

434 Kogo N, Tazaki A, Kashino Y, Morichika K, Orii H, Mochii M, Watanabe K (2011) Germ-line mitochondria exhibit suppressed resp ...