Artemisinin and Nitric Oxide Mechanisms and Implications in Disease and Health

69 As comparison with untreated CIAA mice, pretreatment by ART (60 μg/ml) or RAP (30 μg/ml) for three days, or posttreatment by ...

70 5 ART for Anti-inflammation We noticed that either CFA or LPS upregulates HIF-1α, VEGF, and iNOS, and ART or ART + BLA downre ...

71 CIAA modeling in mice not only requires heat-killed bacteria-containing CFA to potentate CII’s immune stimulation, but also s ...

72 5 ART for Anti-inflammation relationship between NO and SpO 2 established in our study strongly supports that NO is a driver ...

73 posttreatment by ART or RAP can only partially alleviate the severity of inflam- mation. Interestingly, combined posttreatmen ...

74 5 ART for Anti-inflammation Biniecka M, Kennedy A, Ng CT, Chang TC, Balogh E, Fox E, Veale DJ, Fearon U, O’Sulliban JN (2011) ...

75 Kasuno K, Takabuchi S, Fukuda K, Kizaka-Kondoh S, Yodoi J, Adachi T, Semenza GL, Hirota K (2004) Nitric oxide induces hypoxia ...

76 5 ART for Anti-inflammation Paquet J, Henrionnet C, Pinzano A, Vincourt JB, Gillet P, Netter P, Chary-Valckenaere I, Loeuille ...

77 Witthoft T, Eckmann L, Kim JM, Kagnoff MF (1998) Enteroinvasive bacteria directly activate expression of inducible nitric oxi ...

79 Abstract ART can mimic CR to extend yeast lifespan, during which both ART and CR-triggered NO can activate antioxidative resp ...

80 6 ART for Antiaging cGMP for activating NOS and producing NO, through which mitochondrial bio- genesis is evoked and lifespan ...

81 nematodes (Vellai et al. 2003 ), fruit flies (Kapahi et al. 2004 ), and mice (Selman et al. 2009 ). By inactivating mTOR, RAP ...

82 6 ART for Antiaging including COX to simulate the NO-COX interaction. It is believed that CR enables the synchronous decrease ...

83 To disclose the involvement of H 2 O 2 in yeast lifespan extension, we treated yeast cells by different concentrations of H 2 ...

84 6 ART for Antiaging Table 6.1 Up/downregulation of genes responsible for anabolism/catabolism of some major metabolites by CR ...

85 As a major kind of energy metabolites, glucose is regenerated through gluconeogenesis and degraded through glycolysis. Becaus ...

86 6 ART for Antiaging amino acids, cysteine and methionine, are downregulated, whereas degrada- tion pathway genes for two kind ...

87 activity were monitored in pretreated and post-treated yeast cells. After treat- ments, cellular detoxification-related ATP-b ...

88 6 ART for Antiaging 6.2.2.6 Expression Fluctuations of Oxidative Phosphorylation and Antioxidation Responsible Genes: Dual-Ph ...

89 As experimental evidence supporting above suggestion of H 2 O 2 as a main type of ROS, we investigated the expression modes a ...