Exercise for Cardiovascular Disease Prevention and Treatment From Molecular to Clinical, Part 1

265 supporting their conclusion of reduced fibrogenesis included decreased expression of tissue inhibitor of metalloproteinase-1 ...

266 Exercise is a potent stimulator that activates numerous downstream cascades at the molecular and cellular levels. When exerc ...

267 Smith CL, Baek ST, Sung CY et al (2011) Epicardial-derived cell epithelial-tomesenchymal transition and fate specification ...

268 Bostrom P, Mann N, Wu J et al (2010) C/EBPbeta controls exercise-induced cardiac growth and protects against pathological c ...

© Springer Nature Singapore Pte Ltd. 2017 269 J. Xiao (ed.), Exercise for Cardiovascular Disease Prevention and Treatment, Advan ...

270 1 Introduction Cardiovascular disease (CVD) remains the leading cause of death in the world. The dramatic clinical events, s ...

271 [ 16 ]. These factors are able to recruit inflammatory cells to the vessel wall, which in turn can induce cascade expression ...

272 Being able to regulate the activity of cytokines may contribute to the protective effect of physical exercise [ 32 , 33 ]. T ...

273 systems, which may cause tissue injury. It can produce endothelial dysfunction and accelerate atherosclerosis in patients wi ...

274 Endothelial cell integrity is crucial for preserving vascular homeostasis. It allows the continuous adjustment of vascular t ...

275 will start to express cell adhesion molecules (CAMs), such as ICAM-1, VCAM-1, E-selectin, and P-selectin. They are all essen ...

276 2.6 Physical Exercise Preserves Atherosclerotic Plaque Stability Most of the acute coronary syndrome (ACS) occurs because of ...

277 3 Physical Exercise, Can One Overdose? With all the evidence above, the agreement that physical exercise can be applied to t ...

278 Acknowledgements This work was supported by the grants from Shanghai Key Discipline Construction Grant (ZK2012A40) and Natio ...

279 Chernyavskiy I, Veeranki S, Sen U et al (2016) Atherogenesis: hyperhomocysteinemia inter- actions with LDL, macrophage func ...

280 Goldhammer E, Tanchilevitch A, Maor I et al (2005) Exercise training modulates cytokines activity in coronary heart disease ...

281 Rector RS, Warner SO, Liu Y et al (2007) Exercise and diet induced weight loss improves measures of oxidative stress and in ...

282 Tsai JC, Perrella MA, Yoshizumi M et al (1994) Promotion of vascular smooth muscle cell growth by homocysteine: a link to a ...

283 Gielen S, Erbs S, Linke A et  al (2003) Home-based versus hospital-based exercise pro- grams in patients with coronary arte ...

284 Zeiher AM, Goebel H, Schachinger V et al (1995) Tissue endothelin-1 immunoreactivity in the active coronary atherosclerotic ...