Exercise for Cardiovascular Disease Prevention and Treatment From Molecular to Clinical, Part 1

244 7 Moderate Exercise Training (MET) and Stabilization of Nrf2-Antioxidant Signaling in the Myocardium Given the role of Nrf2 ...

245 8 Endurance Exercise Impairs Nrf2-Antioxidant Signaling in the Aging Heart The strategy of endurance exercise has been propo ...

246 endurance training is considered to be safe in aging and regarded as a countermea- sure for aging [ 186 ]. Typically, endura ...

247 combination can affect catecholamine regulation that when inappropriately managed, can result in improper calcium handling l ...

248 Sandvik L, Erikssen J, Thaulow E et  al (1993) Physical fitness as a predictor of mortality among healthy, middle-aged Norw ...

249 Li J, Pang Q (2014) Oxidative stress-associated protein tyrosine kinases and phosphatases in Fanconi anemia. Antioxid Redox ...

250 Wu J, Xia S, Kalionis B et al (2014) The role of oxidative stress and inflammation in cardio- vascular aging. Biomed Res In ...

251 Torella D, Rota M, Nurzynska D et  al (2004) Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth fa ...

252 Jain A, Lamark T, Sjøttem E et al (2010) p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive f ...

253 Lewis KN, Wason E, Edrey YH et al (2015) Regulation of Nrf2 signaling and longevity in naturally long-lived rodents. Proc N ...

254 Safdar A, de Beer J, Tarnopolsky MA (2010) Dysfunctional Nrf2-Keap1 redox signaling in skeletal muscle of the sedentary old ...

255 Conraads VM, Beckers P, Bosmans J  et  al (2002) Combined endurance/resistance training reduces plasma TNF-alpha receptor l ...

© Springer Nature Singapore Pte Ltd. 2017 257 J. Xiao (ed.), Exercise for Cardiovascular Disease Prevention and Treatment, Advan ...

258 1 Introduction Over the last half-century, numerous scientific and clinical reports have examined the relationship between c ...

259 2 Cardiac Remodelling and Fibrosis Cardiomyocytes, fibroblasts, and vascular cells in the heart are connected by an elaborat ...

260 infarctions, and due to the limited regenerative capacity of the heart muscle, repre- sents myocardial healing. In contrast, ...

261 3 Molecular Biology of Cardiac Remodelling and Fibrosis Fibroblasts represent an essential and dynamic cell population in th ...

262 Gene expression often requires the participation of specific transcription factors. Transcription factors are a wide variety ...

263 lysine readers, and histone methylation  - are reviewed in Stratton and McKinsey (2016) [ 34 ]. It is worth noting that, to ...

264 has been demonstrated to make important improvements in skeletal muscle function, glucose homeostasis, respiratory muscle st ...