Exercise for Cardiovascular Disease Prevention and Treatment From Molecular to Clinical, Part 1

224 Strom CC, Aplin M, Ploug T et al (2005) Expression profiling reveals differences in met- abolic gene expression between exe ...

225 Mendoza MC, Er EE, Blenis J (2011) The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation. Trends Biochem Sci 36:3 ...

226 Ramasamy R, Oates PJ, Schaefer S (1997) Aldose reductase inhibition protects diabetic and nondiabetic rat hearts from ische ...

227 Cox EJ, Marsh SA (2013) Exercise and diabetes have opposite effects on the assembly and O-GlcNAc modification of the mSin3A ...

228 Segal BH, Grimm MJ, Khan AN et al (2012) Regulation of innate immunity by NADPH oxidase. Free Radic Biol Med 53:72–80 Xu Q, ...

229 Husain K, Hazelrigg SR (2002) Oxidative injury due to chronic nitric oxide synthase inhibi- tion in rat: effect of regular ...

230 Wang P, Li CG, Qi Z et  al (2016) Acute exercise stress promotes ref/Nrf signaling and increases mitochondrial antioxidant ...

© Springer Nature Singapore Pte Ltd. 2017 231 J. Xiao (ed.), Exercise for Cardiovascular Disease Prevention and Treatment, Advan ...

232 brain, etc. Nevertheless, thus far, only a few studies have described the potential role of Nrf2 and its non-pharmacological ...

233 care costs due to spending on emergency care, hospital care, treatment, rehabilita- tion etc. for the patients and the depen ...

234 reduces the risk of CVD [ 11 , 12 ]. Further, exercise training and physical activity have been shown to increase the longev ...

235 signaling being a common denominator for aging and several cardiovascular dis- eases such as heart failure, stroke, myocardi ...

236 transport, maintenance of barrier function and permeability), smooth muscle cells (responsible for peripheral resistance to ...

237 Notably, cardiac aging in the murine model is highly consistent with the age- related cardiac changes observed in a healthy ...

238 reactions [ 94 ]. These antioxidant factors are supplied to the human system either by endogenous process or through the die ...

239 several genes containing the antioxidant response element (ARE) binding motif due to the high similarity of consensus sequen ...

240 cardiomyocytes can make the myocardium more susceptible to stress, aging, diseases and other toxic insults [ 123 – 125 ]. A ...

2 41 regulation) of Nrf2 with respect to different mode of exercises such as acute exercise stress (AES), endurance exercise str ...

242 Table 13.1 Different modes of exercise and their effects on cardiac health in rodents vs. human Model Description Protocol E ...

243 defense mechanisms leads to reduced cardiac performance, dysfunction, fibrotic remodeling, and inflammation through sustaine ...