Systems Biology (Methods in Molecular Biology)

Alternatively, this equation is equivalent todn/dt1/n¼1/ τ, and the latter relation shows that the equation is equivalent to th ...

wherekis the maximum of the population. Let us remark that we have written the equation in two different forms, we come back on ...

the point of view of classical mechanics. The difficulty lies in the forces exerted by cells as cells can consume free energy to ...

l List the theoretical principles that are relevant to the phenome- non. These principles can be properly biological and pertain ...

l Asymptotic reasoning is a fundamental method to study models. The underlying idea is that models are always a bit complicated. ...

l Special cases. In some situations, qualitatively remarkable beha- viors appear for specific values of the parameters. Studying ...

used to do so on top of a direct verification of the assumptions of the model themselves. Of course, it is never possible to ver ...

The choice between a model based on discrete or on continu- ous time is base on several criteria. For example, if the prolifer- ...

The number of quantities that form the state space is called its dimension. The dimension of the phase space is a crucial matte ...

Microbiol 11(2):83–94.https://doi.org/10. 1038/nrmicro2939 Camalet S, Duke T, Julicher F, Prost J (2000) Auditory sensitivity p ...

Chapter5 TheSearchforSystem’sParameters Alessandro Giuliani Abstract The analysis of biological data asks for a delicate balance ...

coefficients of the independent variables combinations in the fitted model. While each parameter “per se” can have a great uncer ...

specific choice of statistical units whose degree of mirroring of the reference population is unknown [4]. As an example of the ...

we said above, the best antidote against irrelevance of our findings [6]. Pearson continues: “In nearly all the cases dealt with ...

directions along which the between variables correlation is maxi- mal. This implies the projection of the original data set into ...

The material common to all the discrete approaches is the raw data matrix: each exploration of nature ends up into a matrix havi ...

Thus, we contemporarily measure the gene expression level of 24 enzymes involved in the process selected in order to get a good ...

components. This interpretation stems from the previous knowl- edge of the phenomenon at hand, and thus naturally involves “subj ...

terms this means that the motion of the center of mass is the main component of the observed dynamics. PC2 instead has both posi ...

The same “balance” character is present in PC3. The two genes most affected by PC3 (higher loadings in absolute value) are PolB ...