Infectious Agents Associated Cancers Epidemiology and Molecular Biology
214 13.3 PrP Is Pro-survival for Cells One of the important characteristics of cancer cell is its ability against cell death. Ma ...
215 cells to prevent cell death. To determine if PrP is a cellular component response to neuronal injury in vivo, Weise et al. ...
216 is due to PrP that prevents necrosis, autophagy, or apoptosis induced by ischemia. The underlying mechanism for PrP protecti ...
217 ligands of either Toll-like receptors or Fas, as well as phagocytosis by macrophages [ 75 , 76 ], whereas the content of PrP ...
218 WT mice showed more severe infiltration of inflammatory cells in the brain, accom- panied by higher activation of microglia ...
219 the doppel/VEGFR2 axis by an orally active glycosaminoglycan (LHbisD4) specifi- cally represses tumor angiogenesis, thus red ...
220 Burgess STG, Shen C, Ferguson LA, O’Neill GT, Docherty K, Hunter N, Goldmann W (2009) Identification of adjacent binding si ...
221 Li C, Yu S, Nakamura F, Pentikainen OT, Singh N, Yin S, Xin W, Sy MS (2010) Pro-prion binds filamin A, facilitating its int ...
222 Kuwahara C, Takeuchi AM, Nishimura T, Haraguchi K, Kubosaki A, Matsumoto Y, Saeki K, Matsumoto Y, Yokoyama T, Itohara S, On ...
223 Bounhar Y, Zhang Y, Goodyer CG, LeBlanc A (2001) Prion protein protects human neurons against Bax-mediated apoptosis. J Bio ...
224 Tsutsui S, Hahn JN, Johnson TA, Ali Z, Jirik FR (2008) Absence of the cellular prion protein exacerbates and prolongs neuro ...
© Springer Nature Singapore Pte Ltd. 2017 225 Q. Cai et al. (eds.), Infectious Agents Associated Cancers: Epidemiology and Molec ...
226 14.1 Introduction Murine gammaherpesvirus 68 (MHV68) is a naturally occurring virus that was originally isolated from Slovak ...
227 lymphoid tissue [ 13 , 24 , 25 ]. CD25-mediated IL-2 signaling also is necessary for the CD8+ T cell mononucleosis that occu ...
228 14.2.2 MHV68-Associated Fibrosis Several reports associate EBV infection with idiopathic pulmonary fibrosis (IPF), a chronic ...
229 significant changes in cytokines and chemokines in spleens. In contrast, a dramatic increase in T and B lymphocytes in perip ...
230 The impact of MHV68 infection in other mouse models of autoimmune disease also has been evaluated. For instance, IL10−/− mic ...
231 controlled settings. In contrast, analogous studies of GHV infections in humans would require the presence of naturally occu ...
232 Acknowledgments This work was supported by the grant (CA167065, J.C.F) from the National Cancer Institute of the National In ...
233 Park S, Buck MD, Desai C, Zhang X, Loginicheva E, Martinez J, Freeman ML, Saitoh T, Akira S, Guan JL, He YW, Blackman MA, H ...
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