Nucleic Acids in Chemistry and Biology
LTR retrotransposons are sub-divided on the basis of gene order and sequence similarity into the Ty1- copiagroup and the gypsygr ...
retroviruses have been recognised as particularly specialised forms of eukaryotic transposon. In effect they are retrotransposon ...
J.J. Champoux, DNA topoisomerases: Structure, function and mechanism. Ann. Rev. Biochem., 2001, 70 , 369–413. J. Carbon, Yeast ...
A. Sancar, DNA excision repair. Ann. Rev. Biochem., 1996, 65 , 43–81. U. Hubscher, G. Maga and S. Spadari, Eukaryotic DNA polym ...
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CHAPTER 7 RNA Structure and Function CONTENTS 7.1 RNA Structural Motifs 253 7.1.1 Basic Structural Features of RNA 254 7.1.2 Bas ...
254 Chapter 7 RNA sequences also contain sufficient information to fold themselves into specific shapes with distinct chemical p ...
RNA Structure and Function 255 Figure 7.2 Hydration of RNA in the major (a) and minor (b) grooves in the crystal structure of th ...
256 Chapter 7 N N N N N C 1 ' N N N N C 1 ' O N N H N N N O NH 2 C 1 ' a N N N N O N C 1 ' N N C 1 ' N O N N C 1 ' N N O N b H H ...
ribosomal subunit contains a striking diversity of RNA triple interactions, one of which involves a network of hydrogen bonds th ...
258 Chapter 7 Figure 7.7 The secondary and tertiary structure of a loop–loop interaction. Coaxial stacking is preserved in a “ki ...
They can interact with RNA through “outer-sphere” contacts that are mediated by coordinated water molecules (Figure 7.11a). The ...
260 Chapter 7 assemble usually into a unique folded structure. However, this process is very sensitive to reaction condi- tions, ...
RNA Structure and Function 261 Figure 7.10 The ribose-zipper motif in RNA packing. (a) The 2-OH group is bifunctional, serving ...
262 Chapter 7 Figure 7.11 Metal ions in RNA tertiary structure. Direct interactions between RNA and divalent cations can take tw ...
structures of the complete 70S ribosome,^28 a complex of many proteins and 3 RNAs, as well as the 30S and 50S ribosomal subunits ...
Similarly, once an mRNA transcript has been completely synthesized, its 3terminus must be protected through the process of poly ...
RNA Structure and Function 265 O Base O OH P O O O O Base O OH O 5' O Base O OH P O O O Base O OH O O O Nuc H O Base OH OH P O O ...
266 Chapter 7 Figure 7.19 The four classes of RNA splicing either be stitched together sequentially, or certain exons can be ski ...
Group I and group II introns are common in lower eukaryotes, such as fungi and yeast, although the lat- ter is abundant in plant ...
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