Nucleic Acids in Chemistry and Biology

One of the big advantages of AFM for the structural analysis of biological samples is that it can image non-conducting surfaces ...

purpose-developed small cantilevers, which are able to image faster (2s per image). Smaller cantilevers have high-resonant freq ...

electrospray ionization(ESI) mass spectrometry (MS). Some of the current clinical applications of MS are (a) DNA sequencing,^42 ...

Physical and Structural Techniques Applied to Nucleic Acids 451 Figure 11.17 Matrix-assisted laser desorption/ionization time-of ...

452 Chapter 11 Figure 11.18 Electrospray ionization mass spectrum (negative mode) of oligodeoxyribonucleotide d(GCGTTCCCC- CTTTG ...

or unstable structures. Molecular modelling also provides a method to relate the structural, dynamic and thermodynamic propertie ...

the motion over the next time step determined and so on. This process allows ‘uphill’motion over the energy surface, and barrier ...

References V.A. Bloomfield, D. Crothers and I. Tinoco, Physical Chemistry of the Nucleic Acids.Harper and Row, New York, 1974. ...

V.A. Bloomfield, D.M. Crothers and J.I. Tinoco (eds), Nucleic Acids Structures, Properties, and Functions.University Science Bo ...

S. Berkenkamp, F. Kirpekar and F. Hillenkamp, Infrared MALDI mass spectrometry of large nucleic acids. Science, 1998, 281 , 260 ...

http://www.ebook3000.com ...

A:T base pair minor groove electrostatic potential 361 structure 7 abacavir 130 acceptor stem tRNA structure 275, 420 2-acetylam ...

460 Subject Index base pair (contd) separation 349 Watson-Crick 17 bases amino-imino forms 299 electrostatic interactions 34 ket ...

Subject Index 461 DNA (contd) chain terminators 168 chips 184 circular 46–49 copying 223–235 cross-links 301, 330 double strand ...

462 Subject Index DNA structure (contd) I-motif 54 linear polynucleotide 4 non-canonical 52 palindromes 40, 41, 385, 392 sequenc ...

Subject Index 463 G-tetrad G-quartet 53 guanine base structure 14 nucleoside & nucleotide 15–16 guanine, 7-alkyl apurinic si ...

464 Subject Index major groove (contd) agents (contd) TATA-binding protein, TBP 395 electrostatic potential 254 protein binding ...

Subject Index 465 DNA binding 361, 362, 364 nicotinamide adenine dinucleotide (NAD+) structure 112 Nirenberg, M. molecular biolo ...

466 Subject Index oligonucleotide (contd) gapmer 196 immune response 196 insertions 189 mixmer 196 reagents & therapeutics 1 ...

Subject Index 467 double strand break 416 DNA-binding by protein loops Rel & Stat proteins 396 DNA-protein binding kinetic a ...