Innovations_in_Molecular_Mechanisms_and_Tissue_Engineering_(Stem_Cell_Biology_and_Regenerative_Medicine)
116 Kocher AA, Schuster MD, Szabolcs MJ et al (2001) Neovascularization of ischemic myocar- dium by human bone-marrow-derived a ...
117 Zhao T, Zhang Z-N, Rong Z, Xu Y (2011) Immunogenicity of induced pluripotent stem cells. Nature 474(7350):212–215. doi: 10. ...
118 Allogeneic heart stem cells to achieve myocardial regeneration—full text view. [Internet]. Available from: https://clinical ...
119 Wei K, Serpooshan V, Hurtado C et al (2015) Epicardial FSTL1 reconstitution regenerates the adult mammalian heart. Nature 5 ...
© Springer International Publishing Switzerland 2016 121 J. Wilson-Rawls, K. Kusumi (eds.), Innovations in Molecular Mechanisms ...
122 Advances in neuroregenerative strategies are largely hindered by the complexity of the injury or disease pathology. For exam ...
123 7.2 Manipulation of the Glial Scar Local infl ammation is an immediate consequence of neural injury and may lead to progress ...
124 7.2.2 Controlled Release of chABC In spite of promising results, diffusion of chABC into deep regions of the spinal cord and ...
125 anti-Nogo-A treatment in a rodent model of stroke (7 days after infarct) signifi cantly decreased infarct volume in comparis ...
126 7.3.1 Administration of Cytokines, Growth Factors, and Neurotrophic Factors to Modulate Infl ammation Cytokines are released ...
127 disruption of myelin sheaths) [ 72 , 82 ]. TNFα induces this degeneration via the acti- vation of microglia at the injury si ...
128 macrophages and astrocytes after penetrating brain injury was signifi cantly reduced in IL-1R KO mice as compared to wild ty ...
129 hypoxia/hypoglycemia in spinal cord neurons [ 105 – 107 ]. Although current studies were performed on motor neurons, these r ...
130 and FGF-2 administered in combination have been shown to ameliorate neuroin- fl ammation in an experimental model of epileps ...
131 [ 136 ]. In addition to leukocyte infi ltration modulation, Lipitor may also reduce axonal degeneration, myelin degeneration ...
132 similar fashion to Rolipram, demonstrates favorable outcomes in experimental models of stroke due to its ability to suppress ...
133 administration 48 h post-insult increased angiogenesis [ 174 ]. Interestingly, routes of administration may also infl uence ...
134 of FGF-2 [ 179 ]. These VEGF-mediated molecular and cellular changes have been observed by some to correlate with improvemen ...
135 human mesenchymal stem cells (MSCs) genetically modifi ed to overexpress BDNF augmented neuroprotection and axonal sprouting ...
136 increased OPC generation, enhanced survival of dopaminergic neuronal cul- tures, and protection from toxicity [ 213 ]. In st ...
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