A Textbook of Clinical Pharmacology and Therapeutics

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PART V THE RESPIRATORY SYSTEM ...

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CHAPTER 33 THERAPY OF ASTHMA, CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) AND OTHER RESPIRATORY DISORDERS PATHOPHYSIOLOGY OF AS ...

an antibiotic (e.g. co-amoxiclavorclarithromycin), if bacterial infection is strongly suspected – beware potential interactions ...

4.Leukotriene receptor antagonists (e.g. montelukast) are used in adults and children for long-term maintenance therapy and can ...

sufficient to cause expectoration. At this stage, there need be no disability and measures such as giving up smoking (which may ...

cascade of enzymes (see Figure 33.3). This causes a wide var- iety of effects including: relaxation of smooth muscle including ...

METHYLXANTHINES Use Aminophylline(theophylline, 80%; ethylene diamine, 20%) is occasionally used intravenously in patients with ...

Drug interactions Although synergism between β 2 -adrenergic agonists and theo- phyllinehas been demonstrated in vitro, clinical ...

240 THERAPY OF ASTHMA,COPD AND OTHER RESPIRATORY DISORDERS Table 33.2:Comparative pharmacology of some inhaled glucocorticostero ...

use in asthma has declined considerably, with the efficacy of the leukotriene receptor antagonists. ANTI-IGE MONOCLONAL Ab Omali ...

for many patients. Codeinedepresses the medullary cough centre and is effective as are pholcodineanddextromethor- phan, other op ...

α 1 -antitrypsin deficiency, neutrophil elastase destroys the alveolar wall, leading to early-onset emphysema which is rapidly p ...

Currie GP, Srivastava P, Dempsey OJ, Lee DK. Therapeutic modula- tion of allergic airways disease with leukotriene receptor anta ...

PART VI THE ALIMENTARY SYSTEM ...

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●Peptic ulceration 247 ●Oesophageal disorders 252 ●Anti-emetics 253 ●Inflammatory bowel disease 255 ●Constipation 256 ●Diarrhoea ...

ulcer recurrence and complications following successful eradi- cation of the organism. It has been shown that the speed of ulcer ...

With regard to drug therapy, several drugs (see below) are effective. Documented duodenal or gastric ulcerations should be trea ...